Inflammation Can't Explain Depression's Link to Heart Disease Print E-mail

Depression is known to hike the risk of cardiovascular disease, but don't put all the blame on any concurrent rise in inflammation.

So concludes a study led by Dr. Viola Vaccarino, a professor of medicine at Emory University, in Atlanta.

That means that it's back to the drawing board in terms of unraveling the depression-heart disease link, according to Vaccarino.

"That depression is a factor in cardiovascular disease is clear. What is not clear is what kind of mechanism is involved," she said.

The Emory group, as well as researchers from five other medical institutions, studied the possible role of inflammation in a group of 559 women who were referred for heart tests because of blockage in a coronary artery. All the women had a standard test for depression at the start of the study and were followed for an average of about six years.

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