Antidepressants Boost GI Bleeding Risk Print E-mail
Antidepressant drugs called selective serotonin reuptake inhibitors (SSRIs), which include Celexa, Paxil, Prozac and Zoloft, can double the risk of gastrointestinal bleeding, and the threat is more than six times higher if patients take aspirin and similar pain medications at the same time as SSRIs, a new study finds. 

"Clinicians who prescribe these medications should be aware of the potential risk and may need to consider alternatives," senior researcher Dr. Sonal Singh, assistant professor of internal medicine at Wake Forest University School of Medicine, in Winston-Salem, N.C., said in a prepared statement.

His team published the findings in the journal Alimentary Pharmacology & Therapeutics.

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