Like most people with depression and other mental illnesses, Keris Myrick, 46, had trouble at work. In one job, at a university, she asked her boss for a flexible schedule as she coped with a relapse. "My depression was like a tumbleweed, getting bigger and bigger," Myrick recalls. "Then I went into the hospital."

When she came back to work two weeks later, things were not going well. She was on a new drug that made her feel tired, and she didn't think she could work her morning hours. She contacted the Office of Disability Employment Policy in Washington, D.C., about her rights, which she broached in a letter to the university's HR department. But she wasn't able to arrive at a solution and eventually found a new job. "It was a nightmare," she says.

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